One Last Thing with Emmy Rossum















02/15/2013 at 04:30 PM EST



Emmy Rossum stars in Shameless, but did you know the 26-year-old actress also has a solo album out now? Catch her on the big screen for the upcoming Beautiful Creatures as well! This week she sat down to chat with PEOPLE:

Last vacation I took
I went to the Amangani resort in Wyoming for a week with my mom and best friend. We played in the snow and learned all about mating habits of the native animals. I just watched sheep and took pictures!

Last greeting card I sent
I don't think I've sent one since I was about 12, and it was probably on Valentine's Day. I usually use JibJab, where you put your face in a little online thing. People are usually horrified and delighted at the same time. Joan Cusack and her kids taught me.

Last discovery
Etsy. It's such a time suck. I'm buying all these vintage brooches to use as hair ornaments, decoration, every-thing. They make it very easy; it doesn't feel like you're really even purchasing things. It's a better eBay.

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Study: Fish in drug-tainted water suffer reaction


BOSTON (AP) — What happens to fish that swim in waters tainted by traces of drugs that people take? When it's an anti-anxiety drug, they become hyper, anti-social and aggressive, a study found. They even get the munchies.


It may sound funny, but it could threaten the fish population and upset the delicate dynamics of the marine environment, scientists say.


The findings, published online Thursday in the journal Science, add to the mounting evidence that minuscule amounts of medicines in rivers and streams can alter the biology and behavior of fish and other marine animals.


"I think people are starting to understand that pharmaceuticals are environmental contaminants," said Dana Kolpin, a researcher for the U.S. Geological Survey who is familiar with the study.


Calling their results alarming, the Swedish researchers who did the study suspect the little drugged fish could become easier targets for bigger fish because they are more likely to venture alone into unfamiliar places.


"We know that in a predator-prey relation, increased boldness and activity combined with decreased sociality ... means you're going to be somebody's lunch quite soon," said Gregory Moller, a toxicologist at the University of Idaho and Washington State University. "It removes the natural balance."


Researchers around the world have been taking a close look at the effects of pharmaceuticals in extremely low concentrations, measured in parts per billion. Such drugs have turned up in waterways in Europe, the U.S. and elsewhere over the past decade.


They come mostly from humans and farm animals; the drugs pass through their bodies in unmetabolized form. These drug traces are then piped to water treatment plants, which are not designed to remove them from the cleaned water that flows back into streams and rivers.


The Associated Press first reported in 2008 that the drinking water of at least 51 million Americans carries low concentrations of many common drugs. The findings were based on questionnaires sent to water utilities, which reported the presence of antibiotics, sedatives, sex hormones and other drugs.


The news reports led to congressional hearings and legislation, more water testing and more public disclosure. To this day, though, there are no mandatory U.S. limits on pharmaceuticals in waterways.


The research team at Sweden's Umea University used minute concentrations of 2 parts per billion of the anti-anxiety drug oxazepam, similar to concentrations found in real waters. The drug belongs to a widely used class of medicines known as benzodiazepines that includes Valium and Librium.


The team put young wild European perch into an aquarium, exposed them to these highly diluted drugs and then carefully measured feeding, schooling, movement and hiding behavior. They found that drug-exposed fish moved more, fed more aggressively, hid less and tended to school less than unexposed fish. On average, the drugged fish were more than twice as active as the others, researcher Micael Jonsson said. The effects were more pronounced at higher drug concentrations.


"Our first thought is, this is like a person diagnosed with ADHD," said Jonsson, referring to attention deficit-hyperactivity disorder. "They become asocial and more active than they should be."


Tomas Brodin, another member of the research team, called the drug's environmental impact a global problem. "We find these concentrations or close to them all over the world, and it's quite possible or even probable that these behavioral effects are taking place as we speak," he said Thursday in Boston at the annual meeting of the American Association for the Advancement of Science.


Most previous research on trace drugs and marine life has focused on biological changes, such as male fish that take on female characteristics. However, a 2009 study found that tiny concentrations of antidepressants made fathead minnows more vulnerable to predators.


It is not clear exactly how long-term drug exposure, beyond the seven days in this study, would affect real fish in real rivers and streams. The Swedish researchers argue that the drug-induced changes could jeopardize populations of this sport and commercial fish, which lives in both fresh and brackish water.


Water toxins specialist Anne McElroy of Stony Brook University in New York agreed: "These lower chronic exposures that may alter things like animals' mating behavior or its ability to catch food or its ability to avoid being eaten — over time, that could really affect a population."


Another possibility, the researchers said, is that more aggressive feeding by the perch on zooplankton could reduce the numbers of these tiny creatures. Since zooplankton feed on algae, a drop in their numbers could allow algae to grow unchecked. That, in turn, could choke other marine life.


The Swedish team said it is highly unlikely people would be harmed by eating such drug-exposed fish. Jonsson said a person would have to eat 4 tons of perch to consume the equivalent of a single pill.


Researchers said more work is needed to develop better ways of removing drugs from water at treatment plants. They also said unused drugs should be brought to take-back programs where they exist, instead of being flushed down the toilet. And they called on pharmaceutical companies to work on "greener" drugs that degrade more easily.


Sandoz, one of three companies approved to sell oxazepam in the U.S., "shares society's desire to protect the environment and takes steps to minimize the environmental impact of its products over their life cycle," spokeswoman Julie Masow said in an emailed statement. She provided no details.


___


Online:


Overview of the drug: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html


Read More..

Wall Street ends slightly down, S&P positive for seventh week

NEW YORK (Reuters) - The S&P 500 dipped in a late decline on Friday as Wal-Mart dropped following a report of a weak start to February sales, though the index just barely extended its streak of weekly gains to seven.


Equities were little changed for much of the session, with investors finding few reasons to make big bets following an extended rally on Wall Street, but stocks turned lower in afternoon action.


Wal-Mart Stores Inc dropped 2.1 percent to $69.30 after Bloomberg News reported a weak start to February sales, citing internal company e-mails. The stock was the biggest decliner on the Dow, while the S&P retail index <.spxrt> fell 0.5 percent.


"When a retailer of this size comes out with this kind of lousy news, the whole market can fall off, especially on a Friday afternoon," said Mike Shea, trader at Direct Access Partners in New York. "However, I'm not worried that this is indicative of any larger macro issue with retail."


Equities have struggled for direction recently, with major indexes moving only slightly in the past several sessions. The S&P didn't end a session with a move greater than 0.2 percent at all this week.


The benchmark index, up 6.6 percent so far this year, is facing strong technical resistance near the 1,525 level. But investors, expecting the index to advance further in the quarter, have held back from locking in profits.


"There's no news that suggests the strong underpinning for stocks isn't appropriate. We may have gotten ahead of ourselves, but there's also an absence of bad news," said Mark Luschini, chief investment strategist at Janney Montgomery Scott in Philadelphia.


Many investors are starting to look ahead to a debate in Washington over sequestration, automatic across-the-board spending cuts put in place as part of a larger congressional budget fight. The cuts are due to kick in March 1 unless lawmakers agree to an alternative.


"This had been far enough out to not yet become an impediment for stocks, but it will start to move into the forefront and cause people to take a bit of a jaundiced eye towards the market," said Luschini, who helps oversee about $54 billion in assets.


The Dow Jones industrial average <.dji> was up 11.27 points, or 0.08 percent, at 13,984.66. The Standard & Poor's 500 Index <.spx> was up 0.32 points, or 0.02 percent, at 1,521.70. The Nasdaq Composite Index <.ixic> was up 1.51 points, or 0.05 percent, at 3,200.17.


For the week, both the Dow and Nasdaq fell 0.1 percent while the S&P rose 0.1 percent in its seventh straight week of gains, a period during which the index rose 8.4 percent. The last such seven-week run was between December 2010 and January 2011.


The New York Federal Reserve said manufacturing in New York state expanded for the first time in seven months, while Thomson Reuters/University of Michigan's preliminary reading of consumer sentiment rose from the prior month and beat expectations.


But U.S. manufacturing fell in January after a rise in the prior month.


Wall Street's gain thus far in 2013 has largely been driven by strong corporate earnings, while data indicated some weakening in economic conditions.


A surge in merger and acquisition activity, with more than $158 billion in deals announced so far in 2013, has given further support to the equity market as it points to healthy valuations and bets on the economic outlook.


Herbalife shares cut earlier gains to rise 1.2 percent to $38.74. Late Thursday, billionaire investor Carl Icahn said in a regulatory filing that he now owns 13 percent of Herbalife and was ready to put it in play.


MeadWestvaco Corp climbed 12.5 percent to $35.65 as the biggest percentage gainer on the S&P index after activist investor Nelson Peltz's Trian Fund Management LP said it had bought about 1.6 million shares of the packaging company.


Burger King Worldwide shares gained 4.7 percent to $17.36 after it beat estimates with a 94 percent rise in fourth-quarter profit, thanks to new menu additions.


Oil service stocks declined, weighed by a 5.1 percent drop in shares of Transocean to $56.26, after the rig contractor reported its fleet update and Deutsche Bank cut its rating on the stock to "sell." The PHLX oil service sector <.osx> lost 1.5 percent.


Slightly more stocks fell than rose on the New York Stock Exchange while about 50 percent of Nasdaq shares ended lower. About 6.69 billion shares changed hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, above the daily average so far this year of about 6.48 billion shares.


(Editing by Nick Zieminski)



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The Lede: Teenager Killed as Bahrain Marks Protest Anniversary

Video posted on YouTube by activists in Bahrain showed a man confronting riot police officers after a young protester was shot and killed in the village of Al Daih on Thursday.

A Bahraini teenager was shot and killed during clashes with the kingdom’s security forces on Thursday, as protesters marked the second anniversary of the start of their movement calling for reforms on the Arab island.

Both rights activists and the interior ministry reported the young man’s death in the village of Al Daih, outside Manama, the capital. The Bahrain Center for Human Rights posted an image of a death certificate online that said Hussein Ali Ahmed, 16, was killed at 8:30 a.m. on Thursday by gunshot.

The rights group also added the young man’s name to a list of 88 fatalities since the protest movement began two year ago. According to the center, whose founder and current president have both been jailed for their part in the protest movement, 88 people have died since Feb. 14, 2011, including three police officers.

After the young man was shot, local activists uploaded graphic video and distressing photographs of the frantic attempts to save his life, despite a gaping wound in his chest.

One image posted online later was said to show the dead boy’s blood on a man’s shirt.

In another, a woman pushed a shopping cart filled with spent tear gas canisters fired at protesters during the clashes in the village.

Maj. Gen. Tariq Hassan Al Hassan, Bahrain’s chief of public security, acknowledged the death of a “rioter” in a statement that blamed protesters for “several incidents of violent attacks on police officers, attacks on citizens, destruction of property and blocking of roads.”

The police chief’s statement also defended the actions of his officers as necessary since the presence of protesters on the roads of the kingdom impeded the flow of traffic.

Police responded to restore order and clear roads. Traffic flowed freely in the vast majority of areas throughout the day.

When necessary, the police employed proportionate force to disperse violent crowds. Most incidents involved small groups of rioters who were quickly dispersed before they could amass into larger groups. During some of these dispersals, several police officers were injured. Some were injured severely and required hospital care.

The most violent group amassed at around 8 a.m. in the village of Daih, where 300 rioters assembled to attack police, who were deployed in the area, with rocks, steel rods and Molotov cocktails. Warning shots were fired but failed to disperse the advancing crowd who continued their attack. Officers discharged birdshot to defend themselves. At least one rioter was injured in the process. A short time later, a young man was pronounced dead at Salmaniya Medical Center.

The statement said that the death would be investigated and conveyed the police chief’s condolences to the family, while adding that he had “advised young men to avoid taking part in violent street activities and riots,” the day before.

International human rights groups have criticized Bahrain’s use of force in its crackdown on dissent.

Ahmed Al-haddad, who handles international relations for the Bahrain Center for Human Rights, posted an image on Twitter of what he said was an Italian-made shotgun used by the security forces to fire at demonstrators.

Thirteen of the country’s most prominent dissidents remain in jail after being convicted by a military tribunal of trying to overthrow the government. As our colleague Kareem Fahim reported last month, a court upheld their sentences of between five years and life in prison for their leadership roles in the protest movement.

The protests and clashes before and after the fatal shooting in Al Daih were extensively documented in photographs and video posted online by activist bloggers. In several photographs, protesters could be seen holding up cameraphones as they marched.

Mazen Mahdi, a Bahraini photojournalist, wrote on Twitter that he and other photographers were briefly detained while covering the protests.

Video posted online by activists later on Thursday showed the street fighting between rock-throwing protesters and officers who fired tear gas, shotgun pellets and stun grenades. Another raw clip showed a tense confrontation after the fatal shooting between an emotional man and riot police officers.

Activists posted more video online late Thursday that appeared to show the protesters regrouped on the streets after dark and chanted, “The People Want to Topple the Regime!”

Video posted online by activists in Bahrain appeared to show protesters on the streets of Al Daih on Thursday night.

Clashes south of the capital, in Sitra and Nuwaidrat, were also documented on video by activists calling themselves the Media Center for the Revolution in Bahrain (who add titles to their clips and what seems to be introductory music copied from videos posted online by The Associated Press).

In the video from Sitra, a police vehicle appeared to catch fire after protesters hurled Molotov cocktails at it.

The group’s footage of a clash in Nuwaidrat showed small numbers of protesters and the security forces facing off across flaming barricades

The monarchy’s police force continued its aggressive use of social media to combat perceptions that its use of violence in response to protests is disproportionate. The official interior ministry Twitter feed on Thursday featured two video clip uploaded to a police YouTube account on Thursday of “thugs” hurling Molotov cocktails at officers. One of the clips was recorded last week, the police said, the second was undated.

The police did not explain why these previously recorded video clips were not posted on YouTube until the day of the protest movement’s anniversary and did not immediately reply to a request for comment from The Lede.


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Diem Brown Blogs: Will You Be My Valentine?















02/14/2013 at 04:45 PM EST



I honestly cannot begin to express the emotions I felt last week. I have never felt so loved and cared for in my life. I actually started feeling guilty because I didn't know how to express my thanks to everyone who has read this blog, commented on here or on Facebook, Tweeted me, etc.

I felt an army of support that was with me through this whole "cancer" time. When you're in the midst of dark, stress-filled moments, it's hard to comprehend how many people out there are either going through the same/similar thing or want to help support you while you are in your fight.

Once last week's blog went up, my heart was overfilled with love and gratitude for y'all. THANK YOU from the bottom of my heart, thank you so very much for your sweet congratulations and encouraging words. I don't know how to repay you, but will try to brainstorm and find brilliant ways to do so.

This may seem weird, but I feel a connection with so many people who have left comments or Tweeted me about their own struggles and shared their stories. I feel we have this cool community of people that support one another and it lifts my heart.

Given that it's Valentine's Day, I wish I could drop those cool lil' Valentine's Day cards, the ones that have the lollipop attached, into your tin foiled decorated V-Day shoe boxes ... you remember like the ones we used to make in kindergarten.

So ... Will you be my Valentine?

I feel on Cloud Nine right now! I know I won't get that 100% cancer-free card, but I know I am not going anywhere! The remaining tests/chemo treatments, etc. are just precaution. It feels unreal to have this "Go live your life" card, and I want to live it up to the very fullest!

One of my closest girlfriends, Alicia Quarles, happens to be the New York correspondent for E! News, and we started laughing about how we react so differently with good and bad news.

When I was first diagnosed with ovarian cancer in June, I was very stoic during my interview with Alicia. I didn't want to "break" in fear that I couldn't put myself together again. Alicia, on the other hand, whom I have known since college, couldn't help but tear up as she said, "It's just not fair" while she asked questions about my second battle with ovarian cancer.

Cut to last week and Alicia interviewed me this time about my cancer remission news. As soon as I started talking, my voice cracked and all of the emotions I held back in the first interview came out and tears trailed down my face. It was that moment I realized "I am alive and am not going anywhere!"

Diem Brown Blogs: Will You Be My Valentine?| Celebrity Blog, Health, Diem Brown

Diem Brown

Matt Sayles / Invision

I had been so scared that seeing 2014 wasn't going to happen for me that hearing the news that you don't have an "expiration date" makes your whole body release ... happy tears included. Alicia was so excited about my remission news that her smile was beaming as she tilted her head laughing and asked, "Those are happy tears, right?"

I never understood the "happy tears" thing until that moment. I laughed as I begun to dry my wet cheeks saying, "Yeah they are! Now, how do you make these suckers stop flowing?"

I hope everyone experiences a "happy tears" moment, as it's the oddest but most wonderful feeling in the world!

So on this beautiful Valentine's Day I also want you to know that you have an army of people who love you. You might not be able to see it, but you affect more people than you will ever realize. Trust me, put yourself and your heart out there for friends, family, and even for support groups online. Some of the people who can build you up the most could be people online whom you will never meet.

I know this was a cheesy "love blog," but I feel so alive and I feel this overwhelming gratitude and love for y'all! Thank you, thank you, thank you – and
Happy Valentine's Day!

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Study: Fish in drug-tainted water suffer reaction


BOSTON (AP) — What happens to fish that swim in waters tainted by traces of drugs that people take? When it's an anti-anxiety drug, they become hyper, anti-social and aggressive, a study found. They even get the munchies.


It may sound funny, but it could threaten the fish population and upset the delicate dynamics of the marine environment, scientists say.


The findings, published online Thursday in the journal Science, add to the mounting evidence that minuscule amounts of medicines in rivers and streams can alter the biology and behavior of fish and other marine animals.


"I think people are starting to understand that pharmaceuticals are environmental contaminants," said Dana Kolpin, a researcher for the U.S. Geological Survey who is familiar with the study.


Calling their results alarming, the Swedish researchers who did the study suspect the little drugged fish could become easier targets for bigger fish because they are more likely to venture alone into unfamiliar places.


"We know that in a predator-prey relation, increased boldness and activity combined with decreased sociality ... means you're going to be somebody's lunch quite soon," said Gregory Moller, a toxicologist at the University of Idaho and Washington State University. "It removes the natural balance."


Researchers around the world have been taking a close look at the effects of pharmaceuticals in extremely low concentrations, measured in parts per billion. Such drugs have turned up in waterways in Europe, the U.S. and elsewhere over the past decade.


They come mostly from humans and farm animals; the drugs pass through their bodies in unmetabolized form. These drug traces are then piped to water treatment plants, which are not designed to remove them from the cleaned water that flows back into streams and rivers.


The Associated Press first reported in 2008 that the drinking water of at least 51 million Americans carries low concentrations of many common drugs. The findings were based on questionnaires sent to water utilities, which reported the presence of antibiotics, sedatives, sex hormones and other drugs.


The news reports led to congressional hearings and legislation, more water testing and more public disclosure. To this day, though, there are no mandatory U.S. limits on pharmaceuticals in waterways.


The research team at Sweden's Umea University used minute concentrations of 2 parts per billion of the anti-anxiety drug oxazepam, similar to concentrations found in real waters. The drug belongs to a widely used class of medicines known as benzodiazepines that includes Valium and Librium.


The team put young wild European perch into an aquarium, exposed them to these highly diluted drugs and then carefully measured feeding, schooling, movement and hiding behavior. They found that drug-exposed fish moved more, fed more aggressively, hid less and tended to school less than unexposed fish. On average, the drugged fish were more than twice as active as the others, researcher Micael Jonsson said. The effects were more pronounced at higher drug concentrations.


"Our first thought is, this is like a person diagnosed with ADHD," said Jonsson, referring to attention deficit-hyperactivity disorder. "They become asocial and more active than they should be."


Tomas Brodin, another member of the research team, called the drug's environmental impact a global problem. "We find these concentrations or close to them all over the world, and it's quite possible or even probable that these behavioral effects are taking place as we speak," he said Thursday in Boston at the annual meeting of the American Association for the Advancement of Science.


Most previous research on trace drugs and marine life has focused on biological changes, such as male fish that take on female characteristics. However, a 2009 study found that tiny concentrations of antidepressants made fathead minnows more vulnerable to predators.


It is not clear exactly how long-term drug exposure, beyond the seven days in this study, would affect real fish in real rivers and streams. The Swedish researchers argue that the drug-induced changes could jeopardize populations of this sport and commercial fish, which lives in both fresh and brackish water.


Water toxins specialist Anne McElroy of Stony Brook University in New York agreed: "These lower chronic exposures that may alter things like animals' mating behavior or its ability to catch food or its ability to avoid being eaten — over time, that could really affect a population."


Another possibility, the researchers said, is that more aggressive feeding by the perch on zooplankton could reduce the numbers of these tiny creatures. Since zooplankton feed on algae, a drop in their numbers could allow algae to grow unchecked. That, in turn, could choke other marine life.


The Swedish team said it is highly unlikely people would be harmed by eating such drug-exposed fish. Jonsson said a person would have to eat 4 tons of perch to consume the equivalent of a single pill.


Researchers said more work is needed to develop better ways of removing drugs from water at treatment plants. They also said unused drugs should be brought to take-back programs where they exist, instead of being flushed down the toilet. And they called on pharmaceutical companies to work on "greener" drugs that degrade more easily.


Sandoz, one of three companies approved to sell oxazepam in the U.S., "shares society's desire to protect the environment and takes steps to minimize the environmental impact of its products over their life cycle," spokeswoman Julie Masow said in an emailed statement. She provided no details.


___


Online:


Overview of the drug: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html


Read More..

Wall Street ends slightly higher, helped by acquisitions

NEW YORK (Reuters) - The S&P 500 eked out a small gain for a third straight session on Thursday, helped by a flurry of merger activity, though investors see no catalysts to lift the market further with major averages near multi-year highs.


The market's slowed advance took the S&P 500 to its highest intraday level since November 2007 on Wednesday. While the index notched its third straight day of gains, none was more than 0.2 percent.


Shares of H.J. Heinz Co jumped 20 percent to $72.50 after it said Warren Buffett's Berkshire Hathaway and 3G Capital will buy the food company for $72.50 a share, or $28 billion including debt. Berkshire's class B shares rose 1.3 percent to $99.21.


Also supporting the market was data showing the number of Americans filing new claims for unemployment benefits fell more than expected in the latest week. The CBOE Volatility index <.vix> fell 2.4 percent, dropping to 12.67.


"While I'm not bearish, I don't see many upside motivations at these levels," said Donald Selkin, chief market strategist at National Securities in New York, who cited the low level of the VIX as a sign the market was overbought.


Equities have struggled to break above current levels where they have been hovering for almost two weeks. The S&P 500 is up more than 6 percent so far this year.


"We need to digest some of our gains to go higher, but people are so eager to buy on the dips that we're not even seeing dips anymore. People are just chasing the market higher," said Selkin, who helps oversee about $3 billion in assets.


Stocks fell earlier after a report the euro zone's gross domestic product contracted by the steepest amount since the first quarter of 2009. In addition, Japan's GDP shrank 0.1 percent in the fourth quarter, crushing expectations of a modest return to growth.


The Dow Jones industrial average <.dji> was down 9.52 points, or 0.07 percent, at 13,973.39. The Standard & Poor's 500 Index <.spx> was up 1.05 points, or 0.07 percent, at 1,521.38. The Nasdaq Composite Index <.ixic> was up 1.78 points, or 0.06 percent, at 3,198.66.


Constellation Brands soared 37 percent to $43.75 after AB InBev's deal to take over Mexican brewer Grupo Modelo was revised to grant Constellation perpetual rights to distribute Corona and other Modelo brands in the United States. U.S. shares of AB InBev gained 5.1 percent to $92.77.


American Airlines and US Airways Group said they plan to merge in a deal that will form the world's biggest air carrier, with an equity valuation of about $11 billion. US Airways shares fell 4.6 percent to $13.99.


Weakness in Europe contributed to a 5 percent drop in revenue from the region for Cisco Systems , which nonetheless beat estimates as it reported its results late Wednesday. The company's shares dipped 0.7 percent to $20.99.


General Motors Co reported a weaker-than-expected fourth-quarter profit, also citing bigger losses in Europe alongside lower prices in its core North American market. The stock was off 3.3 percent to $27.73.


Only five more stocks rose than fell on the New York Stock Exchange, while 51 percent of Nasdaq-listed shares closed higher.


Volume was light, with about 6.36 billion shares changing hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, below the daily average so far this year of about 6.48 billion shares.


(Editing by Nick Zieminski and Kenneth Barry)



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Kerry Says He Is Preparing Proposals on Syria Crisis





WASHINGTON — Secretary of State John Kerry said on Wednesday that he had ideas about how to persuade President Bashar al-Assad to agree to a political transition in Syria and planned to raise them on his first foreign trip this month.




“We need to address the question of President Assad’s calculation currently,” Mr. Kerry said after a meeting with Jordan’s foreign minister, Nasser Judeh. “I believe there are additional things that can be done to change his current perception. I’ve got a good sense of what I think we might propose.”


Mr. Kerry did not say what proposals he had in mind. He is expected to travel to the Middle East and Europe, but the trip has not been formally announced.


“I can assure you my goal is to see us change his calculation, my goal is to see us have a negotiated outcome and minimize the violence,” Mr. Kerry said. “It may not be possible. I am not going to stand here and tell you that’s automatic or easily achievable. There are a lot of forces that have been unleashed here over the course of the last months.”


Mr. Kerry made a similar statement during his Senate confirmation hearing last month. Despite his caution that progress might not be possible, the effect of Mr. Kerry’s comments was to heighten expectations for his trip. Mr. Kerry is also expected to try to make headway on the issues dividing the Palestinians and the Israelis and set the stage for President Obama’s trip to Israel next month.


Mr. Kerry’s comment on Syria came a day after Mr. Obama said little about the Syria crisis in his State of the Union address. In that speech, Mr. Obama said he would keep pressure on the Syrian regime, but he did not voice confidence, as he had in his 2012 address, that Mr. Assad would soon be forced to relinquish power.


Mr. Kerry said that Mr. Obama would begin by listening to Israeli and Arab leaders and would not be bringing a major new proposal.


“The president is not prepared at this point in time to do more than listen to the parties, which is why he has announced he is going to go to Israel,” he said.


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Carly Rae Jepsen Reveals Why She's Heartbroken on New Single 'Tonight I'm Getting Over You'






Only on People.com








02/13/2013 at 04:45 PM EST



Heartbreak was far from the theme of Carly Rae Jepsen's catchy, career-launching Grammy-nominated radio hit, "Call Me Maybe" – but in her latest single, the starlet touches on romance gone wrong.

Reliving the past failed relationship that inspired "Tonight I'm Getting Over You," Jepsen, 27, recently explained at PEOPLE's pre-Grammy soiree at Sayers Club in Hollywood, "As an artist, it's fun to explore [my] many sides and sort of go through my experience with love in a more personal way. I hope you haven't experienced it, but I certainly have had that relationship that is on-again, off-again and good and bad."

The singer – who has most recently been dating fellow musician Matthew Koma – goes on to say, "With this particular song, it was sort of that decision that even though [the relationship] is hot and cold, sometimes you've got to move on."

Jepsen, who performed a soulful, acoustic version of the typically upbeat song at the party, sings in the lyrics, "We're not lovers, but more than friends. Put a flame to every single word you ever said. No more crying to get me through. I'll keep dancing 'til the morning with somebody new. Tonight I'm getting over you."

Says Jepsen of the Max Martin-produced tune: "I think it's important to have a bit of a connection to a song that you sing, and there's going to be some grittiness behind it, because otherwise it doesn't come across as sincere. So I do think I tap into those memories in a certain way, but it doesn't make me feel sad. It just makes me feel a little contemplative and in the moment."

The man behind the music has not been revealed – and Jepsen says with a laugh, "It's probably for the best" that he doesn't know it's about him.

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Clues to why most survived China melamine scandal


WASHINGTON (AP) — Scientists wondering why some children and not others survived one of China's worst food safety scandals have uncovered a suspect: germs that live in the gut.


In 2008, at least six babies died and 300,000 became sick after being fed infant formula that had been deliberately and illegally tainted with the industrial chemical melamine. There were some lingering puzzles: How did it cause kidney failure, and why wasn't everyone equally at risk?


A team of researchers from the U.S. and China re-examined those questions in a series of studies in rats. In findings released Wednesday, they reported that certain intestinal bacteria play a crucial role in how the body handles melamine.


The intestines of all mammals teem with different species of bacteria that perform different jobs. To see if one of those activities involves processing melamine, researchers from the University of North Carolina at Greensboro and Shanghai Jiao Tong University gave lab rats antibiotics to kill off some of the germs — and then fed them melamine.


The antibiotic-treated rats excreted twice as much of the melamine as rats that didn't get antibiotics, and they experienced fewer kidney stones and other damage.


A closer look identified why: A particular intestinal germ — named Klebsiella terrigena — was metabolizing melamine to create a more toxic byproduct, the team reported in the journal Science Translational Medicine.


Previous studies have estimated that fewer than 1 percent of healthy people harbor that bacteria species. A similar fraction of melamine-exposed children in China got sick, the researchers wrote. But proving that link would require studying stool samples preserved from affected children, they cautioned.


Still, the research is pretty strong, said microbiologist Jack Gilbert of the University of Chicago and Argonne National Laboratory, who wasn't involved in the new study.


More importantly, "this paper adds to a growing body of evidence which suggests that microbes in the body play a significant role in our response to toxicity and in our health in general," Gilbert said.


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